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ชื่อเรื่องThe evolution of imperfection [electronic resource] : the science of why we aren't and can't be perfect / Laurence D. Hurst.
ชื่อเรื่องเพิ่มเติมScience of why we aren't and can't be perfect
 Science of why we are not and can not be perfect
LC Call #QH447 .H87 2025eb
NLM Call #QU 460
ผู้แต่งHurst, Laurence D., 1965-
หัวเรื่องHuman genome.
 DNA.
 Natural selection.
 Evolution (Biology)
 Genome, Human
 DNA
 Selection, Genetic
 Biological Evolution
 evolution.
 SCIENCE / Life Sciences / Biology.
ISBN0691247412
 9780691247410
 9780691247397
พิมพลักษณ์Princeton : Princeton University Press, [2025]
เชื่อมโยงE-book
ชื่อเรื่องThe evolution of imperfection [electronic resource] : the science of why we aren't and can't be perfect / Laurence D. Hurst.
ชื่อเรื่องเพิ่มเติมScience of why we aren't and can't be perfect
 Science of why we are not and can not be perfect
NLM Call #QU 460
LC Call #QH447 .H87 2025eb
ผู้แต่งHurst, Laurence D., 1965-
ISBN0691247412
 9780691247410
 9780691247397
พิมพลักษณ์Princeton : Princeton University Press, [2025]
หัวเรื่องElectronic books.
เนื้อหาThe problem of DNA -- To begin at the beginning .... how adaptation works -- The great evolutionary roulette wheel -- The nearly-neutral theory and the problem of the bloated genome -- Why rare diseases aren't rare -- Problems with placentas, pregnancy, and perfection -- The evolutionary fight back -- The medical fight back.
หัวเรื่องHuman genome.
 DNA.
 Natural selection.
 Evolution (Biology)
 Genome, Human
 DNA
 Selection, Genetic
 Biological Evolution
 evolution.
 SCIENCE / Life Sciences / Biology.
เชื่อมโยงE-book
ลักษณะทางกายภาพ1 online resource (xv, 265 pages) :illustrations
LDR 04880nmm a2200649 i 4500
001 on1475283853
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007 cr cnu---unuuu
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010__‡a2024034337
020__‡a0691247412‡qelectronic book
020__‡a9780691247410‡q(electronic bk.)
020__‡z9780691247397‡qhardcover
037__‡a22573/cats21528392‡bJSTOR
040__‡aSUTL
05004‡aQH447‡b.H87 2025eb
06000‡aQU 460
072_7‡aSCI‡x008000‡2bisacsh
072_7‡aSCI‡x027000‡2bisacsh
072_7‡aSCI‡x029000‡2bisacsh
08200‡a572.8/6‡223/eng/20241204
1001_‡aHurst, Laurence D.,‡d1965-‡eauthor.
24514‡aThe evolution of imperfection‡h[electronic resource] :‡bthe science of why we aren't and can't be perfect /‡cLaurence D. Hurst.
24630‡aScience of why we aren't and can't be perfect
2463_‡aScience of why we are not and can not be perfect
260_1‡aPrinceton :‡bPrinceton University Press,‡c[2025]
300__‡a1 online resource (xv, 265 pages) :‡billustrations
449__‡aE-book, 2026
504__‡aIncludes bibliographical references and index.
5050_‡aThe problem of DNA -- To begin at the beginning .... how adaptation works -- The great evolutionary roulette wheel -- The nearly-neutral theory and the problem of the bloated genome -- Why rare diseases aren't rare -- Problems with placentas, pregnancy, and perfection -- The evolutionary fight back -- The medical fight back.
520__‡a"This book uncovers the ways natural selection leads to imperfection in humans and the implications of this for our understanding of how evolution works and human biology and health. The simplest version of evolution frames it as a gradual process that leads to constant improvement. This view holds that natural selection drives toward "perfection." Mutations in an organism's genome either harm or help its ability to reproduce; harmful ones don't last while beneficial ones are passed on and spread throughout a population. As Laurence Hurst argues in this book, the reality is far more complicated. This is particularly true for humans at the level of our DNA. Why, for example do we need so many sperm to fertilize one egg? Or why do we have a high rate of genetic disease? And why does much of our DNA appear to be pointless? These imperfections do not make sense when we assume that evolution is a constantly improving process, yet the more scientists study our genome the more they see things that look like imperfections. How, then, are they explained? After carefully introducing readers to what he means by perfection and imperfection and providing basic information about DNA, Hurst provides evidence for why the human genome retains imperfections. He argues that our small populations, high mutation rates, and mode of reproduction leave us vulnerable to all sorts of problems. In dissecting the evolution of our imperfection, Hurst illuminates what scientists are learning about the human genome and why it seems to cause so many issues despite our success as a species. Finally, despite what we might call our "rotten lot," evolutionarily speaking, we have our big brains and medicine to combat genetic disease and, at the end of the book, Hurst reviews what scientists are learning about curing genetically based diseases"--‡cProvided by publisher.
590__‡aAdded to collection customer.56279.3
650_0‡aHuman genome.
650_0‡aDNA.
650_0‡aNatural selection.
650_0‡aEvolution (Biology)
65012‡aGenome, Human
65022‡aDNA
65022‡aSelection, Genetic
65022‡aBiological Evolution
650_7‡aevolution.‡2aat
650_7‡aSCIENCE / Life Sciences / Biology.‡2bisacsh
655_0‡aElectronic books.
77608‡iPrint version:‡aHurst, Laurence D., 1965-‡tEvolution of imperfection‡dPrinceton : Princeton University Press, [2025]‡z9780691247397‡w(DLC) 2024034336
850__‡aSUTCL
85640‡3EBSCOhost‡uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=4078457‡zE-book
910__‡aBiology
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